Other typical side effects included fatigue, headache, muscle pain, chills, joint pain, diarrhea, fever and vomiting - all were seen with Pfizer’s original COVID-19 booster too.Īnd just like with Moderna’s bivalent booster trial, no adverse events were reported in the Pfizer trial, though experts say they will continue to keep an eye on the rare risk of myocarditis in both Pfizer and Moderna booster recipients. Pain at the injection site was also the most common complaint among people boosted with Pfizer’s updated vaccine about 60 percent of trial participants reported it. No severe adverse events were seen.įor comparison’s sake, the five most commonly reported side effects following a dose of Moderna’s original COVID-19 booster were injection site pain, fatigue, headache, muscle pain and joint pain. About 80 percent of trial participants reported it, followed by fatigue, headache, muscle and joint pain, chills, nausea and vomiting, and fever. Pain at the injection site was the most commonly reported side effect among people vaccinated with Moderna’s bivalent omicron booster, CDC data shows. “All of the side effects from a bivalent booster were very similar to what we saw with the regular booster, and even going back to the initial vaccination,” said Andrew Pekosz, a virologist at the Johns Hopkins Bloomberg School of Public Health. Looking at the side effects of boosters in these trials, there were no surprises. Experts don’t expect these minor mutations to have any effect on the vaccine’s safety profile. Instead, they relied on data from the first round of booster shots and from a very similar bivalent COVID-19 vaccine - one that targets the original coronavirus strain and also BA.1, an omicron subvariant that “only differs slightly from BA.4 and BA.5,” said Peter Marks, M.D., director of the Center for Biologics Evaluation and Research at the U.S. (This is not an uncommon process for vaccines that need a strain update, much like the annual flu shot.) Health officials approached the approvals for the retooled omicron boosters, also known as bivalent vaccines, a bit differently this time around, since clinical trials testing the BA.4- and BA.5-specific shots were still happening at the time of their authorization. Here’s what to expect if you go in for the jab. Still, some people have questions about the new omicron boosters, including the side effects they can cause. Children as young as 6 months old are also eligible for an updated booster if they were vaccinated with Moderna. Health officials are recommending that fully vaccinated individuals 5 years and older roll up their sleeves for the added dose of protection against the illness that has taken more than 1.08 million American lives.
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